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International Conference and Exhibition on Nanomedicine and Drug Delivery, will be organized around the theme ““Challenges and Innovations in Nanomedicine and Drug Delivery Research””

NanoDelivery 2017 is comprised of keynote and speakers sessions on latest cutting edge research designed to offer comprehensive global discussions that address current issues in NanoDelivery 2017

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Nanomedicine is simply the application of nanotechnologies in a healthcare setting and the majority of benefits that have already been seen involve the use of nanoparticles to improve the behaviour of drug substances. Today, nanomedicines are used globally to improve the treatments and lives of patients suffering from a range of disorders including ovarian and breast cancer, kidney disease, fungal infections, elevated cholesterol, menopausal symptoms, multiple sclerosis, chronic pain, asthma and emphysema. Nanomedicine has the potential to develop radical new therapies based on an unprecedented control over both intracellular processes and the extracellular environment at the nanometer scale. To create precise solutions for intricate medical challenges in the area of wound healing, tissue regeneration and mitochondrial disease physical scientists, medical doctors, and industrial partners, work closely in the Radboud Nanomedicine Alliance. The National Nanotechnology Initiative expects new commercial applications in the pharmaceutical industry that may include advanced drug delivery systems, new therapies, and in vivo imaging.

  • Track 1-1Scope of Nanomedicine
  • Track 1-2Future aspects of Nanomedicine
  • Track 1-3Nanomedicine for Cardiovascular Diseases
  • Track 1-4Nanomedicine for Lung Diseases
  • Track 1-5Nanomedicine for blood disorders
  • Track 1-6Nanomedicine for CNS
  • Track 1-7Nanomedicine for Gastrointestinal Tract (GI) Diseases
  • Track 1-8Nanomedicine for other disease

Nanodrugs phenomenal advances in nanotechnology and nanoscience have been accompanied by exciting progress in de novo design of nano sized drugs. Nanoparticles with their large space of structural amenability and excellent mechanical and electrical properties have become ideal candidates for high efficacy nanomedicines in both diagnostics and therapeutics. The therapeutic nanomedicines can be further categorized into nanocarriers for conventional drugs and nanodrugs with direct curing of target diseases. Here we review some of the recent advances in de novo design of nanodrugs, with an emphasis on the molecular level understanding of their interactions with biological systems including key proteins and cell membranes. We also include some of the latest advances in the development of nanocarriers with both passive and active targeting for completeness. These studies may shed light on a better understanding of the molecular mechanisms behind these nanodrugs, and also provide new insights and direction for the future design of nanomedicines.

  • Track 2-1Nano Sized Drugs
  • Track 2-2Novel Drugs to Nano Drugs
  • Track 2-3Nanodrugs for Cancer Therapy
  • Track 2-4Nanodrugs for Veterinary Therapeutics
  • Track 2-5Nanodrugs for Medical applications
  • Track 2-6Nanodrugs for Herbal medicines and Cosmetics

Nanomedicine is the medical application of nanotechnology. Nanomedicine ranges from the medical applications of nanomaterials and biological devices, to nanoelectronic biosensors, and even possible future applications of molecular nanotechnology such as biological machines. Using nanoparticle contrast agents, images such as ultrasound and MRI have a favorable distribution and improved contrast. This might be accomplished by self assembled biocompatible nanodevices that will detect, evaluate, treat and report to the clinical doctor automatically. Nanotechnology ("nanotech") is manipulation of matter on an atomic, molecular, and supramolecular scale. The earliest, widespread description of nanotechnology referred to the particular technological goal of precisely manipulating atoms and molecules for fabrication of macro scale products, also now referred to as molecular nanotechnology. A more generalized description of nanotechnology was subsequently established by the National Nanotechnology Initiative, which defines nanotechnology as the manipulation of matter with at least one dimension sized from 1 to 100 nanometers.

  • Track 3-1Carbon Nanotubes
  • Track 3-2Nanobiomechanics and Nanomedicine
  • Track 3-3Bio inspired materials and drug delivery
  • Track 3-4Biosensors and Nanobioelectronics
  • Track 3-5Nanocomposite Microspheres
  • Track 3-6Nano Micro Particles
  • Track 3-7Magnetic Nanoparticles
  • Track 3-8Silver Nanoparticles
  • Track 3-9Gold Nanoparticles
  • Track 3-10Nanoparticles
  • Track 3-11Controled radical polymerization

Nanoparticle technology was recently shown to hold great promise for drug delivery applications in nanomedicine due to its beneficial properties, such as better encapsulation, bioavailability, control release, and lower toxic effect. Despite the great progress in nanomedicine, there remain many limitations for clinical applications on nanocarriers.

Synthesizing nanoparticles for pharmaceutical purposes such as drug preparation can be done in two methods. Bottom up process such as pyrolysis, inert gas condensation, solvothermal reaction, sol-gel fabrication and structured media in which hydrophobic compound such as liposomes are used as bases to mount the drug. Top down process such as attrition / milling in which the drug is chiseled down to form a nanoparticle

To overcome these limitations, advanced nanoparticles for drug delivery have been developed to enable the spatially and temporally controlled release of drugs in response to specific stimuli at disease sites. Furthermore, the controlled self-assembly of organic and inorganic materials may enable their use in theranostic applications. This review presents an overview of a recent advanced nanoparticulate system that can be used as a potential drug delivery carrier and focuses on the potential applications of nanoparticles in various biomedical fields for human health care. A novel process for synthesis of polymericnanoparticles for use in drug delivery applicationsusing the electrospraying technique. The technologyis standardized for synthesis of natural polymer based nanoparticles such as chitosan-gelatin based nanoparticles.

  • Track 4-1Nanocarriers
  • Track 4-2ligands
  • Track 4-3Solid Lipid Nanoparticles
  • Track 4-4Polymeric Nanoparticles
  • Track 4-5Dendrimer Nanocarriers
  • Track 4-6Silica materials
  • Track 4-7Carbon Nanocarriers

Tissue Engineering and Regenerative Medicine is appealing to scientists, physicians, and lay people alike: to heal tissue or organ defects that the current medical practice deems difficult or impossible to cure. Tissue engineering combines cells, engineering, and materials methods with suitable biochemical and physiochemical factors to improve or replace biologic functions. Regenerative medicine is a new branch of medicine that attempts to change the course of chronic disease, in many instances regenerating failing organ systems lost due to age, disease, damage, or congenital defects. The area is rapidly becoming one of the most promising treatment options for patients suffering from tissue failure. This book of Regenerative Medicine and Tissue Engineering fairly reflects the state of the art of these two disciplines at this time as well as their therapeutic application. It covers numerous topics, such as stem cells, cell culture, polymer synthesis, novel biomaterials, drug delivery, therapeutics, and the creation of tissues and organs. The goal is to have this book serve as a reference for graduate students, post-docs, teachers, scientists and physicians, and as an explanatory analysis for executives in biotech and Nano pharmaceutical companies.

  • Track 5-1Neuro Regenerations
  • Track 5-2Physiological properties of engineered tissues
  • Track 5-3Microfluidic driven tissue patterning
  • Track 5-4Bone Marrow Tissue Engineering
  • Track 5-5Mechanical properties of engineered tissues
  • Track 5-6Bioreactor design
  • Track 5-7Cell seeded matrices
  • Track 5-8Biologic scaffolds
  • Track 5-9Biomaterials
  • Track 5-10Tissue printing
  • Track 5-11Organ fabrication
  • Track 5-12Cell-based therapies

Nanoparticles in Biomedicine "Nanoparticles for pharmaceutical purposes are defined by the Encyclopedia of Pharmaceutical Technology as solid colloidal particles ranging in size from 1 to 1000 nm (1m). Nanomaterials hold immense promise for significantly improving existing diagnosis, therapy and designing novel approaches to treat a variety of human ailments. While some of the applications of nanotechnology have been translated into clinical settings, many more potential uses of nanomedicines have been demonstrated in experimental systems. Since a variety of materials can be nanosized, the scope of nanomedicine is also large and may even become larger. At the same time, the impact of nanomaterials on cellular and animal models will need to be carefully evaluated under both acute and chronic exposures at toxicological and pharmacological doses. It is extremely important to evaluate the basic issues such as the fate of nanomaterials in biological systems, and how the cells and tissues react to the exposure of nanomaterials in developing nanomedicines. Combating HIV Mellitin, which is found in bee venom, has been found to kill Human immunodeficiency virus.

  • Track 6-1Permeation Across Biological Barriers
  • Track 6-2Investigating structural aspects of Nano Particles
  • Track 6-3Integrated Photonics and Biosensing
  • Track 6-4Photoluminescent Nanoplatforms
  • Track 6-5Tailoring Plasmon Resonances in Metal Nanospheres
  • Track 6-6Miniaturization of Biochips and Bio Labeling
  • Track 6-7Microbicidal coating for Sterility, General Hygienen and Drug Packing
  • Track 6-8NanoBioanalytics and Diagnostic Techniques
  • Track 6-9Plasmon Resonant Metal
  • Track 6-10Biosafety and in vivo tracking
  • Track 6-11Nanopipette Navigation System

Drug delivery describes the method and approach to delivering drugs or pharmaceuticals and other xenobiotics to their site of action within an organism, with the goal of achieving a therapeutic outcome. Issues of pharmacodynamics and pharmacokinetics are important considerations for drug delivery. Designing and developing novel drug delivery systems, with a focus on their application to disease conditions. Preclinical and clinical data related to drug delivery systems. Drug Delivery and Translational Research is a journal published by CRS, providing a unique forum for scientific publication of high-quality research that is exclusively focused on Drug Development and translational aspects of drug delivery. Drug distribution, pharmacokinetics, clearance, with drug delivery systems as compared to traditional dosing to demonstrate beneficial outcomes. Short-term and long-term biocompatibility of drug delivery systems, host response. Biomaterials with growth factors for stem-cell differentiation in regenerative medicine and tissue engineering. Devices for drug delivery and drug/device combination products.

  • Track 7-1Liposomes
  • Track 7-2Future aspects of Drug Delivery
  • Track 7-3Major Challenges in Drug Delivery
  • Track 7-4Current Features in Drug Delivery
  • Track 7-5Versatile Polymers In Drug Deivery
  • Track 7-6Optimization Techniques in Drug Delivery
  • Track 7-7Formulation and Development
  • Track 7-8Drug Development
  • Track 7-9Partnering Opportunities

The Novel Drug Delivery Systems are the method by which a drug is delivered can have a significant effect on its efficacy. Some drugs have an optimum concentration range within which maximum benefit is derived, and concentrations above or below this range can be toxic or produce no Local Drug Delivery Systems benefit at all. On the other hand, the very slow progress in the efficacy of the treatment of severe diseases, has suggested a growing need for a multidisciplinary approach to the delivery of therapeutics to targets in tissues. From this, new ideas on controlling the pharmacokinetics, pharmacodynamics, non-specific toxicity, immunogenicity, bio recognition, and efficacy of drugs were generated. These new strategies, often called drug delivery systems (DDS), are based on interdisciplinary approaches that combine polymer science, pharmaceutics, bio conjugate chemistry, and molecular biology. On the other hand, this reference discusses advances in the design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, pulmonary, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.

  • Track 8-1Sustained Drug Delivery Systems
  • Track 8-2Intracellular Drug Delivery Systems
  • Track 8-3Magnetically Induced Drug Delivery System
  • Track 8-4Transdermal Drug Delivery Systems
  • Track 8-5Nanoparticulate Drug Delivery Systems
  • Track 8-6Ocular Drug Delivery Systems
  • Track 8-7Targeted Drug Delivery Systems
  • Track 8-8Transmucosal Drug Delivery Systems
  • Track 8-9Modified Drug Delivery Systems
  • Track 8-10Local Drug Delivery Systems
  • Track 8-11Intracellular Drug Delivery Systems

With Smart Drug Delivery Technology the unprecedented progresses of biomedical nanotechnology during the past few decades, conventional drug delivery systems (DDSs) have been involved into smart DDSs with stimuli-responsive characteristics. To enhance their therapeutic effects and reduce the related side effects, active drug molecules should selectively accumulate in the disease area for a prolonged period with high controllability. Drug delivery refers to the approaches, formulations, technologies, and systems for transporting therapeutics in the body as needed to safely and efficiently achieve their desired therapeutic effects. Conventional drug delivery systems  (DDSs) are often accompanied by systemic side effects that mainly attributable to their nonspecific bio-distribution and uncontrollable drug release characteristics. To overcome these limitations, advanced controlled DDSs have been developed to achieve the release of payloads at the target sites in a spatial controlled manner. In comparison to the conventional DDSs, the smart controlled DDSs can effectively reduce the dosage frequency, while maintaining the drug concentration in targeted organs/tissues for a longer period of time. In this sense, the controlled DDSs provide broad insights and fascinating properties for decreasing drug concentration fluctuation, reducing drug toxicities and improving therapeutic efficacy.

  • Track 9-1Transmucosal Drug Delivery Systems
  • Track 9-2Sonophoresis Drug Delivery System
  • Track 9-3Lymphoid Drug Delivery System
  • Track 9-4Insitu Drug Delivery
  • Track 9-5Micelle Drug Delivery
  • Track 9-6Emulgel Drug Delivery
  • Track 9-7Hydrogel in Drug Delivery

Nano pharmaceuticals offer the ability to detect diseases at much earlier stages and the diagnostic applications could build upon conventional procedures using nanoparticles. Nano pharmaceuticals represent an emerging field where the sizes of the drug particle or a therapeutic delivery system work at the Nano scale. In the pharmaceutical industry, a long standing issue is the difficulty of delivering the appropriate dose of a particular active agent to specific disease site. Nano pharmaceuticals have enormous potential in addressing this failure of traditional therapeutics which offers site-specific targeting of active agents. Such precision targeting via Nano pharmaceuticals reduces toxic systemic side effects, resulting in better patient compliance. In today world economy, a pharmaceutical industry faces enormous pressure to deliver high-quality products to patients while maintaining profitability. Therefore pharmaceutical companies are applying nanotechnology to enhance or supplement drug target discovery and drug delivery. Nano pharmaceutical reduces the cost of drug discovery, design & development and enhances the drug delivery process.

  • Track 10-1Nanoliposome
  • Track 10-2Drug Targeting
  • Track 10-3Challenges and advances in NanoPharmaceuticals
  • Track 10-4NanoPharmaceuticals from the bench to Scale up
  • Track 10-5Future aspects of NanoPharmaceuticals

Nano biotechnology is a discipline in which tools from nanotechnology are developed and applied to study biological phenomena. For example, nanoparticles can serve as probes, sensors or vehicles for biomolecule delivery in cellular systems. Nano biotechnology covers all aspects of research and emerging technologies including, but not limited to: Fundamental theories and concepts applied to biomedical-related devices and methods at the micro- and Nano-scale (including methods that employ electrokinetic, electrohydrodynamic, and optical trapping techniques), Micromachining and Microfabrication tools and techniques applied to the top-down approach to Nano biotechnology, Nanomachining and Nanofabrication tools and techniques directed towards biomedical and biotechnological applications (e.g. applications of Atomic Force Microscopy, Scanning Probe Microscopy and related tools), Colloid chemistry applied to Nanobiotechnology (e.g. cosmetics, suntan lotions, bio-active nanoparticles), Microtechnologies such as Lab-on-Chip applied to pharmaceutical, biomedical and biotechnological applications, Techniques for probing cell physiology, cell adhesion sites and cell-cell communication, Molecular self-assembly, including concepts of supramolecular chemistry.

  • Track 11-1Bionanoparticle
  • Track 11-2Biologically inspired nanodevices
  • Track 11-3Bionanoparticle Imaging in cells and tissue
  • Track 11-4Biosynthesis of nanoparticles
  • Track 11-5Biomimetic Nanopores
  • Track 11-6Nano Bio Interactions
  • Track 11-7Bio Nanoscience
  • Track 11-8Bio Pharma Industry
  • Track 11-9Bionano Interface in Human Plasma
  • Track 11-10Biomineralization

 The Global Nano Pharmaceutical Industry report gives a comprehensive account of the Global Nano Pharmaceutical market. Details such as the size, key players, segmentation, SWOT analysis, most influential trends, and business environment of the market are mentioned in this report. Furthermore, this report features tables and figures that render a clear perspective of the Nano Pharmaceutical market. The report features an up-to-date data on key companies’ product details, revenue figures, and sales. Furthermore, the details also gives the Global Nano Pharmaceutical market revenue and its forecasts. The business model strategies of the key firms in the Nano Pharmaceutical market are also included. Key strengths, weaknesses, and threats shaping the leading players in the market have also been included in this research report. Nanotechnology, the science of very small materials, is poised to have a big impact in pharmaceutical packaging. Basic categories of nanotechnology applications and functionalities appear in development of pharmaceutical Packaging(or pharma) in terms of enhancement of plastic materials’ barriers; incorporation of active components that can deliver functional attributes beyond those of conventional active packaging and sensing and signaling of relevant information.

  • Track 12-1Industrial Applications of Nano medicine
  • Track 12-2Nanotechnology tools in Pharmaceutical R&D
  • Track 12-3Bio Pharmaceutical Industry
  • Track 12-4Focus on Nanopharmaceuticals
  • Track 12-5An Up and Coming Market for Nanotechnology

Nanomedicines have been in the forefront of pharmaceutical research in the last decades, creating new challenges for research community, industry, and regulators. There is a strong demand for the fast development of scientific and technological tools to address unmet medical needs, thus improving human health care and life quality. Tremendous advances in the biomaterials and nanotechnology fields have prompted their use as promising tools to overcome important drawbacks, mostly associated to the non-specific effects of conventional therapeutic approaches. However, the wide range of application of nanomedicines demands a profound knowledge and characterization of these complex products. Their properties need to be extensively understood to avoid unpredicted effects on patients, such as potential immune reactivity. Research policy and alliances have been bringing together scientists, regulators, industry, and, more frequently in recent years, patient representatives and patient advocacy institutions. In order to successfully enhance the development of new technologies, improved strategies for research-based corporate organizations, more integrated research tools dealing with appropriate translational requirements aiming at clinical development, and proactive regulatory policies are essential in the near future. This review focuses on the most important aspects currently recognized as key factors for the regulation of nanomedicines, discussing the efforts under development by industry and regulatory agencies to promote their translation into the market.

  • Track 13-1Nanomedicine: Prospects, Risks and Regulatory Issues
  • Track 13-2Current , Future Applications and Regulatory challenges
  • Track 13-3Regulatory Principles and Perspectives
  • Track 13-4Research Policy and Alliances
  • Track 13-5Regulatory Policies
  • Track 13-6Regulation of Nanomedicines
  • Track 14-1Prospects and Challenges of Graphene
  • Track 14-2Applications of Graphene in Medicine
  • Track 14-3Graphene in biosensors
  • Track 14-4Synthesis of Graphene and 2D Materials
  • Track 14-5Graphene based nanomaterials
  • Track 15-1Nanomaterials for Imaging
  • Track 15-2Hierarchical Nanomaterials for Structural Color
  • Track 15-3Optical sensors
  • Track 15-4Nanostructured Hybrid Aerogel Insulation
  • Track 15-5High Performance Coatings Materials
  • Track 15-6Smart Polymer Nanoparticles
  • Track 15-7Materials for Theranostics
  • Track 15-8Nanomaterials for Diagnostics
  • Track 15-9Advanced Nanomaterials
  • Track 15-10Techniques for characterization in nanotechnology
  • Track 15-11Polymeric nanocomposites
  • Track 15-12Biocompatible nanomaterials
  • Track 15-13Metal Nanoparticle Enhanced Emission

Personalizedmedicine aims to individualize chemotherapeutic interventions on the basis of ex vivo and in vivo information on patient- and disease-specific characteristics. By noninvasively visualizing how well image-guided nanomedicines-that is, submicrometer-sized drug delivery systems containing both drugs and imaging agents within a single formulation, and designed to more specifically deliver drug molecules to pathologic sites-accumulate at the target site, patients likely to respond to nanomedicine-based therapeutic interventions may be preselected. In addition, by longitudinally monitoring how well patients respond to nanomedicine-based therapeutic interventions, drug doses and treatment protocols can be individualized and optimized during follow-up. Furthermore, noninvasive imaging information on the accumulation of nanomedicineformulations in potentially endangered healthy tissues may be used to exclude patients from further treatment. Consequently, combining noninvasive imaging with tumor-targeted drug delivery seems to hold significant potential for personalizing nanomedicine-based chemotherapy interventions, to achieve delivery of the right drug to the right location in the right patient at the right time.

  • Track 16-1Nanomedicine for Cancer
  • Track 16-2NanoMedicine in HIV
  • Track 16-3Drug targeting
  • Track 16-4Image-guided drug delivery
  • Track 16-5Imaging

Nanomedicines in Theranostics are advantageous over standard low-molecular-weight drugs in several different regards. They reduce renal excretion and/or hepatic degradation, leading to prolonged circulation times, reduce the volume of distribution, leading to less accumulation in healthy non-target tissues (‘site-avoidance drug delivery’), improve the ability of drugs to accumulate at pathological sites (‘site-specific drug delivery’) and improve the therapeutic index of drugs, by increasing their accumulation at the target site and/or reducing their localization in potentially endangered healthy organs. In addition, nanomedicine formulations assist low-molecular-weight (chemo-) therapeutic agents in overcoming several additional barriers to efficient drug delivery to pathological sites. We show that theranostic nanomedicines are highly suitable systems for monitoring drug delivery, drug release and drug efficacy. The (pre)clinically most relevant applications of theranostic nanomedicines relate to their use for validating and optimizing the properties of drug delivery systems, and to their ability to be used for pre-screening patients and enabling personalized medicine.

  • Track 17-1Theranostic Targeting Vectors
  • Track 17-2Molecular Therapeutics
  • Track 17-3Image Guided Therapy
  • Track 17-4Biosensors
  • Track 17-5System Biology and Translational Medicine
  • Track 17-6Personalized Medicine
  • Track 17-7Future Theranostic Applications
  • Track 17-8Innovative Applications for Diagnosis