Nanomedicine and Drug Delivery

Biography

Giovanni Ligresti ,Ph. D. is Assistant Professor at Mayo Clinic. He received his Ph.D. from the University of Udine. Previously he also worked at Biogen Idec, University of Washington - Departments of Medicine and Bioengineering, University of Washington - Departement of Pathology. Research Investigator with over 12 years of experience in molecular biology, vascular biology, immunology, tissue fibrosis, and tissue engineering. Lead investigator in several research projects focusing on different aspects of cell biology and disease including tumor growth and metastasis, angiogenesis, vascular rarefaction, tissue injury, and inflammation. Experienced in developing 3D multicellular cultures and tissue organoids in serum free-defined media to study cellular response mechanisms and for drug testing. Experienced in developing complex human 3D cellular systems using microfluidic platforms to study disease dynamics. Extensive experience in most aspects of the drug discovery process including cell signal transduction, target selection and validation, development of in vitro cell-based assays and the design of in vivo preclinical mouse models. Demonstrated abilities of leadership as a group manager and project leader in designing and managing multiple research projects in collaboration with universities, hospitals and health care institutions. Large peer-reviewed publication history in the fields of research oncology, signal transduction biology, vascular biology, immunology, fibrosis and tissue engineering.

Research Interest

Tissue injury and fibrosis research