Shunsaku Kimura
Kyoto University, Japan
Biography
Shunsaku Kimura has his expertise in peptideengineering in providing various kinds of peptide materials. He has invented to prepare molecular assemblies showing various morphologies of planar sheet, vesicle, and tube with homogeneous size distributions. This method is now extended to prepare chimeric morphologies including a round-bottom-shaped morphology which is considered as a combined morphology of vesicle and tube. One of the molecular assembly has been successfully applied for the theranostics of solid tumors, where the nanoparticle is labeled with indium-111 for SPECT imaging and with yttrium-90 for therapy. Breast cancer, bone cancer, brain cancer, and meningeal seeding can be nicely targeted with this nanoparticle. This approach paves a challenging aspect of nanoparticle based on the new concept of molecular design taking immune response into consideration.
Abstract
Abstract : Peptide-based nanoparticles of immune-evasive, immune-tolerable, and immune-active properties