Neeraj Mishra
I.S.F. College of Pharmacy, India
Title: Surface modified microparticulate carriers of Embelin for their beneficial Pharmacological potential in ulcerative colitis
Biography
Biography: Neeraj Mishra
Abstract
Present study was aimed to developed enteric coated microsphere of Embelin and their pharmacological potential was investigated in acetic acid induced ulcerative colitis. The optimized formulation of embelin loaded microspheres has shown significant sustained release of embelin. Further this formulation significantly reduced the ulcer activity score, oxidative stress and attenuates the inflammatory changes. Thus it may be concluded that embelin loaded enteric coated microparticles has shown delayed release capacity than plain Embelin and exerts colon ulcer protective effect in rats.