Saeedeh Ghiasvand
Malayer University,Iran
Title: Bacteriophage: the smallest organisms with Remarkable abilites
Biography
Biography: Saeedeh Ghiasvand
Abstract
The discovery of ligands that selectively bind to a certain target plays a vital role in the generation of clinically relevant diagnostics and therapeutics. Phage display as a powerful methodology has proven very promising in the identification of many target specific ligands. But there is another aspect that phage can act as biomarkers. Phage colonized in the people bodies from the earliest moments of life and become our fellow travelers through the life. Phageome seems to be unique to each individual and alter in each different situations. phagosome structure and composition change depend on the physiological or pathological status of the body. Phageome oriented studies are vital to advance our understanding of the potential roles of phages in clinical application. The identification of phagosome as health or disease biomarker provides novel opportunities for unraveling the mechanisms underlying different diseases, stratifying patients, and developing more effective diagnostic and therapeutic approaches. Recent finding favor the suggestion that the phage might directly (phagosome that colonized in our body) or indirectly ( phage display technology) act as potential biomarkers for diagnosis and treatment.