Hiroshi Maeda
Professor Emeritus
Kumamoto University (Med)
Japan
Biography
Hiroshi Maeda is a world renowned expert in macromolecular therapeutics. He created the world first polymeric-conjugate drug, SMANCS, approved for treatment of hepatoma in Japan. Consequently, he discovered the concept of EPR effect of macromolecular-drugs, ubiquitous mechanism for solid tumor selective targeting of polymeric drugs. He received MS, University of California, Devis, Fulbright student, Ph.D., M.D., Tohoku University. He published more than 450 papers in reputed journals. He was awarded Lifetime-Achievement-Award at Royal-Pharmaceutical-Society, Princess-Takamatsu-Award in Cancer Research, Tomizo-Yoshida-Award, highest award of Japan-Cancer-Assoc., and also selected as most cited influential scientist in pharmacology by Thomson Reuters 2014, and H-index of 89.
Research Interest
Cancer chemotherapy, macromolecular therapeutics (polymer drugs), molecular pathology in cancer and infectious diseases, drug targeting, bacterial infection/ mechanism of pathogenesis of proteases/kallikrein/kinin, role of free radicals/ nitric oxide in infectious diseases and cancer, mutation, cancer prevention