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Zahid Hasan

Zahid Hasan

NCBA&E Main Campus Lahore, Pakistan

Title: Nano medicine: A Novel Model based Coulomb Explosion for the Study of Nano-particles of Gold in the Treatment of Breast Cancer

Biography

Biography: Zahid Hasan

Abstract

Nanotechnologist and medical researchers are still involved in a fighting against a high number of serious and complex diseases like breast cancer. Breast cancer remains a significant global medical issue among all ages of women and need to serious attention in this direction for research, investment, and effective and safely treatment. Traditional treatments including surgery, radiation therapy, chemotherapy, targeted therapy, and hormone therapy are not have effective  results and have many limitations.

In this research work, coulomb explosion model is proposed to design “Heat control system” that will work as heat therapy for the treatment of the fatal cancer cells at molecular and Nano atomic level on the bases of “See and Treat” using Nano heat sensors and Nano Cameras. For controlling the intensity of heat we used the magical properties of coated Gold Nano- Particles with less than 100nm in our proposed research work. The gold nanoparticles are irradiated with a laser beam to initiate Coulomb explosion. The resulting explosion generates a high-energy shockwaves, which causes damage to the cancer cells and leads to their destruction by controlling the intensity of heat to induce hyperthermia, which involves heating the cancerous tissue to a temperature between 41-45°C to selectively kill the cancer cells. The heat control system has several advantages over traditional cancer treatments such as chemotherapy or radiation therapy. Firstly, hyperthermia can selectively target cancer cells, leaving healthy tissue unharmed. Secondly, it can be combined with other cancer treatments to enhance their effectiveness. Finally, it is a non-invasive procedure that is well-tolerated by patients.

Moreover we used the finite element method to simulate the temperature distribution in the breast tissue during the treatment. This proposed model will be evaluated on the Thermo Phoresis Nt. The numerical results obtained in graphical form and show how Nano-particles of Gold preserve their energy as well as how they can be used in the treatment of cancer cells.  The results are obtained by using MATLAB simulation.