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2nd International Conference and Exhibition on Pharmaceutical Nanotechnology and Nanomedicine, will be organized around the theme “Navigating the Future of Nanomedicine & Nanotechnology”
Nano Pharmaceuticals 2019 is comprised of keynote and speakers sessions on latest cutting edge research designed to offer comprehensive global discussions that address current issues in Nano Pharmaceuticals 2019
Submit your abstract to any of the mentioned tracks.
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Nanomedicine is a branch of medicine that applies the knowledge and tools of nanotechnology in the prevention and treatment of diseases. Nanomedicine involves the use of nanoscale materials, such as biocompatible nanoparticles and Nano robots, for diagnosis, delivery, sensing or actuation purposes in a living organism. Nanoparticles with ~100 nanometers have been widely used to improve the drug accumulation, internalization and therapeutic efficacy. The physicochemical and biological properties of the Nanoparticles can also be finely adjusted by tailoring their chemical properties, sizes, shapes, structures, morphologies, and surface properties. Nanomedicine is the medical application of Nanotechnology. Nanotechnology has provided the possibility of delivering drugs to specific cells using nanoparticles. Current problems for nanomedicine involve understanding the issues related to toxicity and environmental impact of nanoscale materials.
Nanomedicine seeks to deliver a valuable set of research tools and clinically useful devices in the near future.The National Nanotechnology Initiative expects new commercial applications in the pharmaceutical industry that may include advanced drug delivery systems, new therapies, and in vivo imaging.
- Track 1-1Regenerative Medicine
- Track 1-2Nanocarriers for CNS Drug Delivery
- Track 1-3Neurodegenerative Disorders
- Track 1-4Inorganic Nanoparticles
- Track 1-5Nanochemistry
Pharmaceutical Nanotechnology based system deals with emerging new technologies for developing customized solutions for drug delivery systems. The drug delivery system positively impacts the rate of absorption, distribution, metabolism, and excretion of the drug or other related chemical substances in the body. In addition to this the drug delivery system also allows the drug to bind to its target receptor and influence that receptor’s signaling and activity. Pharmaceutical nanotechnology embraces applications of nanoscience to pharmacy as nanomaterials, and as devices like drug delivery, diagnostic, imaging and biosensor.
- Track 2-1Characterization of Pharmaceutical Nano tools
- Track 2-2Engineering of Pharmaceutical Nanosystems
- Track 2-3Applications of Pharmaceutical Nano tools
- Track 2-4Challenges to Pharmaceutical Nanotechnology
- Track 2-5Future Scope and Prospects of Pharmaceutical Nanotechnology
Nanotechnology seems to have gained a widespread interest in the recent years. Nanotechnology has considerably accelerated the growth of regenerative medicine the past few years. Application of Nanotechnology in regenerative medicine has revolutionized the designing of grafts and scaffolds which has resulted in new grafts/scaffold systems having significantly enhanced cellular and tissue regenerative properties. Since the cell–cell and cell-matrix interaction in biological systems takes place at the nanoscale level, the application of nanotechnology gives an edge in modifying the cellular function and/or matrix function in a more desired way to mimic the native tissue/organ. Nanomedicine introduces Nanotechnology concepts into medicine and thus joins two large cross disciplinary fields with an unprecedented societal and economical potential arising from the natural combination of specific achievements in the respective fields.
- Track 3-1Antibacterial activity
- Track 3-2Nanomedicine and COPD
- Track 3-3Parkinson Disease
- Track 3-4Role in vaccines
- Track 3-5Treatment of breast cancer
- Track 3-6Autoimmune diseases
- Track 3-7Atherosclerosis
Nanotechnology is universally recognized as one of the most important scientific fields of the twenty‐first century. Biomedical applications of this technology offer great promise in finding new approaches to repairing damaged tissues and curing disease. Nanomedicine and Nanobiotechnology will address key topics from the perspectives of medicine, biology, physics, chemistry, and engineering, and serve as an encyclopedic reference for Nanomedicine and Nanobiotechnology research.
- Track 4-1Nanotechnology approaches to biology
- Track 4-2Therapeutic approaches and drug discovery
- Track 4-3Implantable materials and surgical technologies
- Track 4-4Toxicology and regulatory issues
- Track 4-5Diagnostic tools
Nanomedicine will be based on the ability to build Nanorobots. In the future these Nanorobots could actually be programmed to repair specific diseased cells, functioning in a similar way to antibodies in our natural healing processes. The motivation for the new manipulation technology is the desire to enter the micro- and Nanoworld not only by viewing but also acting, altering micro- and nanosized objects. A new era on medicine are expected to happen in the coming years. Due to the advances in the field of Nanotechnology, Nanodevice manufacturing has been growing gradually. The elimination of bacterial infections in a patient within minutes, instead of using treatment with antibiotics over a period of weeks.
- Track 5-1Nanorobots and nanomedicine - future of bioengineering
- Track 5-2Nanorobotic applications in medicine
- Track 5-3Medical nanorobotics
- Track 5-4Nanorobot applications designs and scaling studies
Some smart drug delivery platform is based on neutral phospholipid Nanoliposomes. Where classic Classic liposomes modalities have had manufacturing problems involving sizing, uniformity, loading, storage, and enhancement compatibility, which can be overcome by employing true nanotechnology to build liposomes upon discrete self-assembling DNA scaffolds. The smart drug delivery system is used for delivering drugs to the host. Biological information detected by biological sensors is analyzed and the drug delivery system is actuated to deliver the drug based on the information. MEMS or NEMS technology based drug pumps, micro-pumps, micro-needles, micro-osmotic pumps, and nano-pumps are utilized for smarter drug delivery. One of the concerns these days about self-assembling nanotechnology is that it is so advanced beyond the current drug paradigm that it becomes problematic from a regulatory point of view. While there is currently no drug treatment delivered directly into these types of cancers.
- Track 6-1Wound healing
- Track 6-2Cardiovascular diseases
- Track 6-3Role of nanoparticle mediated drug delivery in metastasis
- Track 6-4Ocular drug delivery
- Track 6-5Insulin delivery
- Track 6-6Neuro-HIV management
- Track 6-7Nanobeads in drug delivery
The computational studies in nanoparticles have demonstrated that there has been considerable progress in nano- and biotechnology in the last several years. However, several key challenges have also become apparent, including the need for a better understanding of nanoparticle behaviour in vivo and the development of more effective nanoparticle therapeutics. Computational efforts are becoming an important tool in addressing both of these challenges, as well as in generally facilitating and accelerating nanotechnology-based translational research. The Nanoinformatics has come out as a new research area that covers raw data management, analysis of the data derived from biomedical applications and simulation of nanoparticle interactions with biological systems depicting the integration of biology, nanotechnology and informatics to form the basis for computational Nanomedicine
- Track 7-1Quantum dots
- Track 7-2Nanoparticles in pharmacokinetics model
- Track 7-3Optical absorption
- Track 7-4Molecular binding properties
- Track 7-5Nanoparticles in mathematical modelling
- Track 7-6Nanoparticles and thermodynamic computations
- Track 7-7Imaging and nanoparticles
- Track 7-8Chemoinformatics
Nanomedicine has been developing rapidly in recent years, particularly in the development of novel nano tools for medical diagnosis and treatment. For instance, a new trend is becoming prevalent in developing Nanosystems for simultaneous tumour diagnosis and therapy. A new terminology "theranostics" has been frequently used and applied in pre-clinical research and trials. A Nanosystem can simultaneously achieve both cell targeted in vivo imaging and photothermal treatment of cancer. While achieving concurrent high spatial and temporal resolution of the lesions via cell targeting; special non-evasive treatments are implemented at the same time by various means, such as localized drug release, hyperthermia, and photo-thermal therapy. Inspired by these challenging problems in biomedical fields, the development of the nanotechnologies will be the key in addressing some of the critical issues in medicine, especially in early cancer diagnosis and treatment.
- Track 8-1Nanotechnology in Nanomedicine
- Track 8-2Explicit and Revolutionary of Nanomedicine
- Track 8-3Development and Application of Ever-Improving Nanotools
- Track 8-4Evolutionary of Nanomedicine
With the remarkable development of Nanotechnology in recent years, new drug delivery approaches based on the state-of-the-art nanotechnology have been receiving significant attention. Nanoparticles, an evolvement of nanotechnology, are increasingly considered as a potential candidate to carry therapeutic agents safely into a targeted compartment in an organ, particular tissue or cell. These particles are colloidal structures with a diameter less than 1,000 nm, and therefore can penetrate through diminutive capillaries into the cell’s internal machinery. This innovative delivery technique might be a promising technology to meet the current challenges in drug delivery. The different types of nanoparticles drug delivery systems under investigation and their prospective therapeutic applications, and also present a closer look at the advances, current challenges, and future direction of nanoparticles drug delivery systems.
- Track 9-1New Drug Delivery Approaches
- Track 9-2Advance combinations of Nanoparticles
- Track 9-3Current Challenges in Drug Delivery
- Track 9-4Nano-Tubes in Medicine and Health Care
- Track 9-5Significance in Neurological Disorder
- Track 9-6Application of Nanoparticles in Pulmonary Diseases
The use of nanoscale materials and processes to address human disease is perhaps the most promising, considering that most complex downstream symptoms of disease are initiated by molecular level phenomena. Nanomedicine is defined as biological and medical intervention at the nanometer scale for the treatment, diagnosis, and increased understanding of biology and disease. Tremendous advances in the area of polymer synthesis and self-assembly have given rise to a new toolbox of engineered nanosized delivery and diagnostic agents that permit systemic and local administration, circulation in the bloodstream, and uptake and diffusion at the cellular and subcellular level.
- Track 10-1Lipid polymer nanoparticles
- Track 10-2Polymer nanomedicine in anti-cancer therapy
- Track 10-3Advances in designing of polymeric nanoparticle
- Track 10-4Surface coating strategies
Recent years have witnessed the rapid development of inorganic nanomaterials for medical applications. At present, nanomedicines-nanoparticles (NPs) destined for therapy or diagnosis purposes-can be found in a number of medical applications, including therapeutics and diagnosis agents .Pushing the limits of nanotechnology towards enhanced Nanomedicines will surely help to reduce side effects of traditional treatments and to achieve earlier diagnosis. The interplay between engineered nanomaterials and biological components is influenced by complex interactions which make predicting their biological fate and performance a nontrivial issue. We hope that both early-stage and experienced researchers will find it valuable for designing nanoparticles for enhanced bio-performance. Nanoemulsions have attracted great attention in research, dosage form design and pharmacotherapy. This is as a result of a number of attributes peculiar to nanoemulsions.
- Track 11-1Frontiers in Drug Design and Discovery
- Track 11-2Enhanced Nanomedicines
- Track 11-3Engineered Nanomaterials and Biological Components
- Track 11-4Nano-Bio Interactions
- Track 11-5Current State of Nanoemulsions in Drug Delivery
Nanotechnology is a rapidly growing field having potential applications in many areas. Nanoparticles have been studied for cell toxicity, immunotoxicity, and genotoxicity. Tetrazolium-based assays such as MTT, MTS, and WST-1 are used to determine cell viability. Different types of cell cultures, including cancer cell lines have been employed as in vitro toxicity models. Considering the potential applications of NPs in many fields and the growing apprehensions of FDA about the toxic potential of Nanoproducts, it is the need of the hour to look for new internationally agreed, free of bias toxicological models by focusing more on in vivo studies. The rapid expansion of nanotechnology promises to have great benefits for society, yet there is increasing concern that human and environmental exposure to engineered nanomaterials may result in significant adverse effects. The system was developed for Nanotoxicity assessment at single and multiple cell levels which can measure and compare the microscopic and macroscopic effects of nanoparticles interaction with cells, without interference from neighbouring cells' cues and also overall integrative effects produced by nanoparticles and cell–cell communication.
- Track 12-1Neonatal toxicity
- Track 12-2Mitochondrial injuries
- Track 12-3Cytotoxicity
- Track 12-4Toxicity to human lymphocytes
- Track 12-5Oral toxicity
- Track 12-6Toxicity due to inhalation of nanoparticles
Currently, the treatment of HIV requires regular oral dosage of HIV drugs, and chronic oral dosing has significant complications that arise from the high pill burden experienced by many patients across populations with varying conditions leading to non-adherence to therapies. Recent evaluation of HIV patient groups have shown a willingness to switch to nanomedicine alternatives if benefits can be shown. Research efforts by the Liverpool team have focused on the development of new oral therapies, using Solid Drug Nanoparticle (SDN) technology which can improve drug absorption into the body, reducing both the dose and the cost per dose and enabling existing healthcare budgets to treat more patients.
- Track 13-1Graphene Medicine
- Track 13-2Image-guided drug delivery
- Track 13-3Nanomedicine for Diabetes
- Track 13-4Autoimmune diseases
- Track 13-5Parkinson Disease
Formulation studies involve developing a preparation of the drug which is both stable and acceptable to the patient. For orally administered drugs, this usually involves incorporating the drug into a tablet or a capsule. It is important to make the distinction that a tablet contains a variety of other potentially inert substances apart from the drug itself, and studies have to be carried out to ensure that the encapsulated drug is compatible with these other substances in a way that does not cause harm, whether direct or indirect. Formulation studies also consider such factors as particle size, polymorphism, pH, and solubility, as all of these can influence bioavailability and hence the activity of a drug. The drug must be combined with inactive ingredients by a method which ensures that the quantity of drug present is consistent in each dosage unit e.g. each tablet. The dosage should have a uniform appearance, with an acceptable taste, tablet hardness, or capsule disintegration. By the time phase III clinical trials are reached, the formulation of the drug should have been developed to be close to the preparation that will ultimately be used in the market.
- Track 14-1Pre Formulation & Formulation Aspects
- Track 14-2Major Challenges in Drug Development
- Track 14-3Preformulation in Drug Development
- Track 14-4Pharmaceutics and Drug Delivery
Pharmacy is the science and technique of preparing and dispensing drugs. It is a health profession that links health sciences with chemical sciences and aims to ensure the safe and effective use of pharmaceutical drugs. A theory relating chemical structure to pharmaceutical activity emerged from the interplay of experimental results from animal and human tests using vaccines, antitoxins, and antibodies with chemical knowledge about dyes and their molecular structures. Although pharmacology is essential to the study of pharmacy, it is not specific to pharmacy. Pharmacoinformatics is considered as another new discipline, for systematic drug discovery and development with efficiency and safety. The progressively more important role of the chemist and chemical science in pharmaceuticals in the early-20th century is mirrored in the history of the American Chemical Society's Division of Medicinal Chemistry
- Track 15-1Biomarkers
- Track 15-2Anticancer roles
Nanomedicines are an emerging product class in the health sector, hence, they have to comply with the high standards of the medicinal product regulation or other related legislative frameworks such as the medical devices regulation. The application of nanotechnology in health care is widely accepted as a potential driver of biomedical innovation. Nevertheless, the opportunities of nanotechnologies in the health sector are accompanied by challenges in the regulation of these products. Sufficient knowledge on their quality, safety, and efficacy must be gained and standardised methods must be made available to support the regulatory decision making and allow a smooth translation towards clinical applications we have conducted a survey among regulatory authorities with the aim to obtain a general overview on the status and regulatory needs of nanomedicines and to indicate some trends on future requirements
- Track 16-1Current, Future Applications and Regulatory challenges
- Track 16-2Regulatory Policies
- Track 16-3Nanomedicine: Prospects, Risks and Regulatory Issues